BEGIN:VCALENDAR
VERSION:2.0
PRODID:Icfo
X-PUBLISHED-TTL:P1W
BEGIN:VEVENT
UID:6a0363cc9f14e
DTSTART:20230904T100000Z
SEQUENCE:0
TRANSP:OPAQUE
DTEND:20230904T110000Z
LOCATION:ICFO Auditorium & Online (Zoom)
SUMMARY:ICFO | JENNIFER LIPPINCOTT - SCHWARTZ
CLASS:PUBLIC
DESCRIPTION:Profile:\nDr. Jennifer Lippincott-Schwartz is a Senior Group Le
 ader at the Howard Hughes Medical Institute&rsquo\;s Janelia Research Camp
 us and Head of the Research Program on 4D Cellular Physiology. Lippincott-
 Schwartz has pioneered the use of green fluorescent protein technology for
  quantitative analysis and modelling of intracellular protein traffic and 
 organelle dynamics in live cells. Her innovative techniques to label\, ima
 ge\, quantify and model specific live cell protein populations and track t
 heir fate have provided vital tools used throughout the research community
 . Her findings using these techniques have reshaped thinking about the bio
 genesis\, function\, targeting\, and maintenance of various subcellular or
 ganelles and macromolecular complexes and their crosstalk with regulators 
 of the cell cycle\, metabolism\, aging\, and cell fate determination. She 
 is an elected member of the National Academy of Sciences\, the National Ac
 ademy of Medicine\, the American Society of Arts and Sciences and the Euro
 pean Molecular Biology Organization. She co-authored the textbook &ldquo\;
 Cell Biology&rdquo\; and was President of the American Society of Cell Bio
 logy. Dr. Lippincott-Schwartz attended Swarthmore College\, received her M
 S from Stanford University\, and obtained her PhD in Biochemistry from Joh
 ns Hopkins University.\nAbstract:\nPowerful new ways to image the internal
  structures and complex dynamics of cells are revolutionizing cell biology
  and bio-medical research. In this talk\, I will focus on how emerging flu
 orescent technologies are increasing spatio-temporal resolution dramatical
 ly\, permitting simultaneous multispectral imaging of multiple cellular co
 mponents. In addition\, results will be discussed from whole cell milling 
 using Focused Ion Beam Electron Microscopy (FIB-SEM)\, which reconstructs 
 the entire cell volume at 4 voxel resolution. Using these tools\, it is no
 w possible to begin constructing a &ldquo\;organelle interactome&rdquo\;\,
  describing the interrelationships of different subcellular organelles as 
 they carry out critical functions. The same tools are also revealing new p
 roperties of organelles and their trafficking pathways\, and how disruptio
 ns of the organelle&rsquo\;s normal functions due to genetic mutations may
  contribute to important diseases.
DTSTAMP:20260512T173052Z
END:VEVENT
END:VCALENDAR